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Articles from 2022 In August


Talent & Techniques

Talent & Techniques: TipLyft: A Safe and Effective Filler-Based Rhinoplasty

Article-Talent & Techniques: TipLyft: A Safe and Effective Filler-Based Rhinoplasty

Talent & Techniques: TipLyft: A Safe and Effective Filler-Based Rhinoplasty

Despite being plagued with many problems in its early years, filler-based rhinoplasty is steadily increasing in popularity. Over a century ago, Francis J. Quinlan, MD, tried injecting paraffin to fix deformities / improve the appearance of the nose. In the 1980s liquid silicone was a popular injectable for this procedure. However, these options failed due to disastrous granuloma formation.

T&T 1.pngIn 1981, the FDA approved bovine collagen filler, which attracted many practitioners to begin performing improvements on the nose and around the face using this material. Unfortunately, the short-lived nature and the potential allergic reactions limited its use. Then came two other fillers: hyaluronic acid and hydroxyapatite.

I started to inject Restylane (Galderma Laboratories) for nose improvement in 2004. The technique I used began by injecting small boluses onto the nasal periosteum/perichondrium to improve the dorsum. I would also inject small boluses onto the surface of the domal cartilage or immediately at the tip of the subdermal layer to avoid vascular compromises. Nevertheless, these techniques did not prove to be trouble-free. From 2004 through 2015, I performed around 3,000 nasal filler injections. The results were mostly successful; however, vascular compromises unavoidably took place. A total of five complications were identified. Every time a vascular compromise occurred, I wished I could quit my job. The psychological burden of disfiguring people was simply unbearable. In addition, the use of hydroxyapatite was also problematic due to its prolonged recovery time and difficulty to inject.

T&T 2.pngThere are six major blood vessels interconnecting in the tiny nasal tip region just under the skin, easily occluded with filler injections. As a result, it became apparent to me that, to avoid these vessels, I would have to utilize some other entry points or spaces in order to successfully inject filler for tip improvement.

A study published in the Plastic & Reconstructive Surgery Journal looked at the histology of the membranous septum, where they found only some scanty capillaries and an abundance of fibrous tissues.1 I used the concepts presented in this article and began injecting fillers into the septal space for tip improvement. I was able to master the techniques for elevating and elongating the nose tip with great efficiency.

T&T 3.pngFor practitioners familiar with the nasal anatomy, the tip is very mobile. If one pulls on the columella, the tip range of motion could shift up to 1 cm upward (elevation) and up to 1 cm caudad (elongation). In the resting state, the columella hugs the caudal septum. However, as the columella is pulled upward or caudad, the membranous septum demonstrates great mobility like that of a “bounce house.” This concept of a “bounce house” is easily understandable because the membranous septum has columella in the front, caudal septal cartilage in the back, and an abundance of fibrous structures bind the two sides of the membranes.

Injection of filler boluses into this area could only lead to the mobile columella/tip structure moving away from the caudal septal cartilage due to the caudal septal cartilage being fixed and the membranes not expanding sideways. Consequently, the tip structure becomes propped up and can be lifted or elongated, as directed by the practitioner. The nose can be elongated up to 6 mm and the tip can be elevated up to 8 mm. These feats were never achievable with any of the techniques previously described.

Compared to the traditional tip injection technique, one of the most prominent features of the TipLyft protocol is the optimization of the infra-tip lobule to columella ratio, which was ignored for decades. Ideally, the lobule to columella ratio (L/C ratio) should be 1:2. However, with traditional tip injection techniques, the filler is simply piled onto the tip, causing a reversal of the lobule to columella ratio and further compressing the nostrils (Figure 1).

With the illustration of traditional filler injection results shown in Figure 1b, it is not a surprise that until now not a single practitioner has published any data or pictures depicting the changes in patients’ nostrils after their nose tip “improvement” from a worm’s eye view.

Nose tip elongation and elevation with TipLyft can be appreciated in Figures 2 and 3.

Many more benefits are observed with the unique TipLyft technique, as described in my original paper Nose Tip Elongation and Elevation: A Novel Filler Injection Technique.2 To date, I have performed more than two thousand TipLyft procedures, without a single vascular compromise. The injection into the septal space deposits the filler boluses far from the skin and columella so there is little risk for a vascular compromise to occur.

In conclusion, TipLyft using high G-prime hyaluronic acid gel is a revolutionary technique. It has disrupted many of the doctrines for filler nose injections. The protocol is safe, easy and extremely efficient. Furthermore, we know that nose tip elongation is hard to achieve, even with surgical maneuvers, but TipLyft easily accomplishes the job. My biggest objective is for this TipLyft technique to encourage more studies to follow, hopefully changing the way that plastic surgeons think about rhinoplasty surgeries.

About the Author

T&T Author.png

Arthur Yu, MD, PhD

Dr. Yu was trained in plastic surgery at Mayo Clinic (Rochester, Minn.); Asian cosmetic surgery with Robert Flowers, MD (Honolulu, Hawaii); head & neck surgery at MD Anderson (Houston, Texas); and general surgery at Brooklyn Hospital (Brooklyn, N.Y.). His main interests are Asian eyelid surgery, Asian rhinoplasty, facial and body contouring with high-definition liposculpturing and stem cell-enriched autologous fat grafting. He prefers minimally invasive approaches to achieve natural results.

References:

1. Lee et al. (Lee MR, Menyoli M, Roostaeian J, Unger JG, Rohrich RJ.) Soft-tissue composition of the columella and potential relevance in rhinoplasty. Plast Reconstr Surg. 2014;134(4):621-625.)

2. Yu AY. Nose Tip Elongation and Elevation: A Novel Filler Injection Technique. Aesthet Surg J. 2022 May 18;42(6):660-676. doi: 10.1093/asj/sjac006).

 

 

IM-Aesthetics Announces AMWC North America

Article-IM-Aesthetics Announces AMWC North America

AMWC North America Logo

For two decades, the Aesthetic & Anti-Aging Medicine World Congress (AMWC) has built a stellar reputation for its highly stimulating, multi-discipline education programs in Monaco, Latin America and Asia. Now, this world-class scientific event is coming to North America (NA) in 2023, making it more accessible than ever to you and your team.

With a scientific program guided by the Aesthetic Multispecialty Society (AMS), featuring a faculty of over 100 key opinion leaders and subject matter experts from around the world, get ready for a global exchange of ideas, intensive education and training in four key areas:

Nonsurgical Aesthetic Treatments & Techniques

Covering the spectrum of minimally invasive aesthetic treatment options, the AMWC NA scientific program features a number of sessions dedicated to both emerging and established nonsurgical aesthetic procedures. These sessions will feature specifics on anatomy, techniques, safety, proven combinations, and complications management, ensuring you leave equipped with the latest updates in nonsurgical therapies.

Minimally Invasive Surgical Procedures

The focus on minimally invasive procedures extends to aesthetic surgery. Within this sphere, you will discover the latest minimally invasive developments and advancements to some of the most in-demand surgical aesthetic procedures, including face and neck treatments, rhino- modulation, and body shaping enhancements, to name a few.

Age Prevention & Specialty Segments

The wide-ranging agenda will also explore specialty segments such as functional and aesthetic sexual well- ness, hair restoration, integrative aesthetics and regenerative medicine – all fast-growing, synergistic sectors of medical aesthetics.

With the aim of treating the underlying causes of aging and alleviating the effects of the aging process, these sessions will draw on global faculty, important case studies and scientific research to bring you culturally diverse approaches to rejuvenation, and provide a comprehensive overview of the scientific advances taking place in anti-aging and aesthetic medicine.

Practice Management & Marketing

Learning how to properly manage your business is essential to running a successful aesthetic practice. The sessions within the practice management track will arm you with the practical tools and knowledge you need to grow your practice. From identifying your unique value proposition to marketing your brand effectively, to staff and reputation management – AMWC NA has you covered.

Plus, A Bustling Exhibit Hall

In addition to the CME-accredited program and practice management sessions, you can get first-hand experience with products and services from more than 100 leading aesthetic companies in the accompanying exhibit hall and Treatment Center.

AMWC is the foremost event focusing on the continuing education of aesthetic practitioners and the fostering of new, meaningful connections. You cannot afford to miss the much-anticipated launch of AMWC NA.

AMWC NA

February 23-25, 2023

Miami Beach Convention Center – Miami, FL

Learn more at www.amwc-na.com

IM-AESTHETICS

Informa Medical Aesthetics (IM-Aesthetics) is a global, multi-channel resource for medical aesthetics that advocates for the continuing education of practitioners worldwide and provides a space for the market to come together. Breaking down international boundaries via in-person and virtual events world- wide, IM-Aesthetics delivers thought-provoking and valuable scientific programs across Europe, Asia, and the Americas, as well as print/digital magazines and international collaborative opportunities that push for the advancement of the field.

AESTHETIC MULTISPECIALTY SOCIETY

The Aesthetic Multispecialty Society (AMS) is the official scientific partner of the IM-Aesthetics’ conference series, including AMWC North America. This international scientific society is run by a committee of recognized global experts in the field of aesthetic and anti-aging medicine. AMS also hosts a digital portal that provides a community of over 16,000 professionals with an online space dedicated to promoting further education and facilitating networking opportunities.

Breaking Barriers: The New Frontier of Sexual Health and Wellness

Article-Breaking Barriers: The New Frontier of Sexual Health and Wellness

Breaking Barriers: The New Frontier of Sexual Health and Wellness

Doctors 1 sexual health and wellness.pngConversations surrounding sexual health and wellness were, until recently, somewhat taboo topics. “Women have always dealt with incontinence, dryness and more, but they did not talk about it because there was not the medium to do so,” said triple board-certified cosmetic surgeon Daisy Ayim, MD (Houston, Texas). However, as society breaks barriers, the dialogue surrounding the look, feel and functionality of the vagina are healthy and inclusive discussions, leaving no woman to feel ashamed or alone.

“It is a sexual revolution for women. They have their needs, and now they can address them,” explained board-certified OB/GYN Russell Bartels, MD, co-founder of VitalityMDs in Scottsdale, Ariz.

Allan Yang Wu, MD, a cosmetic and reconstructive surgeon of Revive Wellness Center in Torrance, Calif., shared, “Baby boomers refuse to compromise on sexual function with maturity while millennials see sexual health as part of normal health. As more healthcare providers realize that sexual function correlates to overall physical and mental health, we move from the traditional doctor’s office to long-term health and wellness,” he continued.

Doctors 2 sexual health and wellness.pngThe demand for treatments that rectify sexual health and wellness issues shows no signs of slowing down. According to data from researchandmarkets.com, the global sexual wellness market will reach $125 billion by 2026. From 2014 to 2019, vaginal rejuvenation treatments (surgical and nonsurgical) jumped 220%, with more than 25% of plastic surgeons offering these therapies.1

Common problems include incontinence, dryness, post-partum effects like a vagina that (to the patient) does not feel or look the same, decreased libido and a loss of sensation and pleasure during intercourse. “These days, there is such a push towards self-care, so why not include treatments that rejuvenate the vagina?” Dr. Ayim proposed.

Two groups of women seek help to correct what bothers them, shared Christine Hamori, MD, a board-certified plastic surgeon from Duxbury, Mass. “Menopausal and post-menopausal women who experience laxity, dryness and incontinence; or patients in their late teens and early 20s who do not like their labia and feel it is bigger than normal,” she continued.

But what is a ‘normal’ vagina, and where do women get the idea that theirs is abnormal? “It is a personal perception, but the media and social media may perpetuate this notion,” Dr. Hamori pointed out.

Hormone Help

Hormones play a crucial role in sexual health and wellness. During menopause and andropause, sex hormone levels decline. Estrogen, progesterone and testosterone levels decrease in women, leading to dryness and diminished libido. Similarly, men also produce less testosterone, which causes a low sex drive and difficulty achieving and maintaining erections.

“Sexual wellness issues almost always arise due to hormones, poor circulation, or the tissue of the sex organ,” explained Samantha Thiry, FNP-C, APRN of Happy Body in Austin, Texas.

As menopause sets in, Ms. Thiry recommends hormone therapies. Treatments include sprays, sublingual tablets, patches, topical and intravaginal creams, pellet therapy, bioidentical hormones and hormone replacement therapy (HRT) injections. “These therapies alleviate menopause-related symptoms to improve quality of life,” she explained.

Picture 1 sexual health and wellness.pngEnergy-Based Treatments

Kim Evans, MD, a board-certified OB/GYN from Sugar Land, Texas, runs a niche practice that caters to female sexual health. She remembers purchasing her first vaginal rejuvenation device in 2014. “Women could not believe there was something like it,” she exclaimed.

Since then, Dr. Evans said there have been changes in the nonsurgical device arena, one being combination therapies to fully address patients’ issues. “There are a lot of nonsurgical solutions that we can use together to help patients – that is a game-changer,” Dr. Evans emphasized.

“Although more devices and handpieces are available, the main technologies remain the same,” Dr. Bartels added.

For as much praise as physicians give nonsurgical devices, in 2018, the FDA issued a warning about their use for vaginal rejuvenation. In anecdotal cases outside the U.S., Dr. Wu reported that laser and RF energy were implicated in stenotic scar tissue formation in the vaginal canal. “There is concern that these complications have resulted from inappropriate use,” he explained. “Coinciding with these events, the FDA took notice of the marketing practices of device companies and whether handpieces, and the power unit, had approval for sexual indications.”

Still, RF devices and CO2 lasers are the go-to solutions for treating lax tissues and muscles, leaky bladder, vaginal dryness and lack of sensation. The energies heat the tissue to activate fibroblasts and stimulate collagen production, healthy blood flow, and improve tightness while internally rejuvenating the vagina for better bladder function and enhancing the vaginal skin. In addition, creating a hyperresponsive vaginal mucosa promotes lubrication and also produces collagen and elastin. “The nerve endings become more responsive and reactive to regain feeling,” Dr. Ayim advised. Both modalities are speedy and well-tolerated with no downtime or discomfort but require maintenance sessions.

Laxity is common amongst menopausal and post-pregnancy women. “I am seeing more women complaining of laxity, which they describe as looseness during intercourse, an open look to the back of the vagina when examining themselves with a mirror, or a vagina that does not look like it did before kids,” Dr. Hamori shared. “Women do not feel the same friction and sensation with intercourse, and they want to improve the sexual experience.”

Picture 2 sexual health and wellness.pngPopular nonsurgical RF treatments to tighten the vagina include ThermiVa RF (Thermi) and the Viveve System (Viveve Medical). EMFEMME 360 from BTL Aesthetics (Boston, Mass.) goes one step further and tracks the tissue’s temperature for a uniform energy delivery. It is also fast – treatment clocks in at eight minutes. “With it, we can adjust the pelvic contractions’ timing, power and strength, and its ergonomic design makes it comfortable for patients,” Dr. Evans noted.

Similar to how EMFEMME 360 monitors the heat, Venus Fiore from Venus Concept (Toronto, Ont., Canada) features an Automatic Temperature Control feature and real-time thermal feedback for safe, consistent results. Multipolar RF and pulsed electromagnetic fields power Venus Fiore, which tightens the labia and reduces the mons pubis. It also creates new blood vessels, collagen and elastin for better sensation, moisture and elasticity.

RF treatments also help with incontinence by improving the tone of the sphincter. “Tightening it controls the urge to urinate,” stated Dr. Ayim. She prefers Inmode’s multimodality Empower RF because, “It works internally to tighten the sphincter to improve incontinence while increasing vaginal lubrication and tightening the vagina.”

Another doctor favorite for treating incontinence (for women and men) is Emsella (BTL Aesthetics), which utilizes electromagnetic energy to strengthen a weak pelvic floor. Flaccid pelvic muscles make it difficult to control the release of urine, and a simple laugh or sneeze can cause leakage. Patients sit clothed on a special chair for 30 minutes for six sessions. The chair delivers energy to the muscles causing them to contract, comparable to doing thousands of Kegel exercises, for better bladder control. “With Emsella, we are treating the problem rather than offering a temporary solution,” Dr. Evans emphasized. According to clinical studies, 95% of Emsella patients report an improved quality of life.

CO2 and erbium:YAG lasers work intravaginally to heat the tissue superficially. Lasers like MonaLisa Touch (DEKA), FemiLift (Alma), Juliet (Cutera) and FemTouch (Lumenis) enhance and thicken the mucosa tissue for improved lubrication. These devices also create microscopic tissue wounds that stimulate a collagen-producing response that increases blood flow. “However, CO2 lasers come with risks like scarring and burning,” warned Dr. Ayim.

A notch down from CO2 laser are hybrid lasers, like DiVa (Sciton). These combine CO2 with erbium for less ablative treatment of delicate vaginal tissue. “Hybrid lasers have a high affinity for water, so they are less destructive to the tissue,” Dr. Ayim clarified.

Ultrasound-based devices, like Cliovana (Cliovana Ltd), are effective for heightened sensitivity. They are not as strong as hybrid or CO2 lasers, yet they are more robust than RF. Cliovana improves sexual responsiveness, as well as orgasm intensity and frequency by creating new blood flow to the clitoris and nerve endings. In addition, it enriches lubrication, so painful sex is less of an issue.

Dr. Bartels says low-intensity soundwave technology, customarily used to treat erectile dysfunction in men, also works for women. Devices like FemiWave (Eclipse) improve blood flow for clitoral enhancement and heightened sensitivity.

Non-invasive options may improve loose labial skin for some, but those with more laxity may need the next step up. “We can do a scarless labiaplasty with InMode’s Aviva,” said Dr. Hamori. This 20-minute, minimally invasive procedure uses heat to reshape the soft tissue of the vulva without excising any skin.

Picture 3 sexual health and wellness.pngInjectables and Shots

Ever since platelet-rich plasma (PRP) showed evidence for regenerative purposes, it has been a mainstay in aesthetics and medicine. The O-shot uses PRP to increase vascularization in the clitoris and vagina for improved sensitivity. “It uses the body’s ability to regenerate to help with moisture and mild incontinence,” shared Dr. Evans.

In the case of moderate laxity with minor incontinence, EMFEMME 360 can be used with the O-shot to tighten the vagina and outer areas. In addition, some physicians couple the O-shot with Emsella to further strengthen the pelvic floor to improve leaking.

Dr. Evans mixes PRP with hyaluronic acid fillers to stimulate collagen and inflate a deflated labia, known as the Vaginal Wing Lift. “We can also combine it with the O-shot for increased sensation,” she added, “or use it to improve volume loss, looseness and discoloration.”

The G-Shot is intended to increase sensitivity in the area of the Grafenburg-spot (G-Spot). Injecting hyaluronic acid filler directly into the G-Spot pushes it downwards for more contact during intercourse, explained Dr. Hamori. “However, it is a vascular area, and there have been reports of the filler traveling to the lungs, so only an expert should perform this,” she cautioned.

Hyaluronic acid injections can also be used to ‘puff out’ the labial tissues, so that the labia appear less wrinkled. Dr. Bartels shared that using filler with RF treatments tightens the external skin further. Fat transfer is another option.

Picture 4 sexual health and wellness.pngLet’s Not Forget the Males

Female sexual health treatments may be seeing an uptick, but men want to remedy their issues, too, which according to Ms. Thiry, are often related to circulation problems. Erectile dysfunction (ED) is a lack of sufficient blood flow to the penis and affects men of all ages. Research shows that 40% of men age 40 and 70% of men age 70 suffer from ED.

In younger patients with poor circulation or performance anxiety, Ms. Thiry suggests shock wave treatments, which break down the arteries and veins in the penile tissue, so they regrow stronger and more capable of proper blood flow. Some shock wave treatments have shown an extremely high success rate (75%) in treating ED based on more than 100 clinical studies, as have devices that use pulsed acoustic sound waves.

Peptide injections, specifically PT141, are being hailed as a magic bullet quick fix. Dr. Bartels says that injecting peptides into the lower abdomen increases libido and sexual response for 24 to 48 hours.

The P-shot, PRP injections into the penile tissue, is the male version of the O-shot for longer-lasting increased circulation, firmness and stamina.

Penis enlargement surgery, which places penile implants under the skin, remains the gold standard for increasing size while treating erectile dysfunction issues. “We can transfer fat to add volume and use dermal fillers, which gradually increase girth and provide some length,” expressed Dr. Wu. To straighten the penis, he shares that XIAFLEX® (collagenase clostridium histolyticum) injections break up scar tissue to reduce erectile curvature.

Picture 5 sexual health and wellness.pngInto the Future

As the sexual health and wellness industry grows, expect new uses of treatments typically reserved for the face and body. For example, Morpheus V8 (microneedling radiofrequency) from InMode is making its way onto other body parts. “It is a new intravaginal microneedling RF device that treats the whole area, including the clitoris, to help with lubrication, incontinence and sensation,” Dr. Hamori revealed.

Nano fat is gaining traction, too, according to Dr. Hamori. “Superficially injecting growth factors derived from fat helps with lichen sclerosus and dryness,” she added.

Dr. Wu and his research team are investigating small molecule screening of FDA-allowed supplements and natural product isolates. One, in particular, is Avogen, which is isolated from avocado. “It has remarkable properties for improving moisture and elasticity in women suffering from menopause-related atrophy,” he shared. “The molecule is neither a steroid nor estrogen related, and we believe it utilizes a novel pathway that could avoid estrogen side effects.”

Dr. Wu disclosed that he is also developing minimally invasive home-based devices that utilize micro-fractionated negative pressure to induce collagen production within the vaginal lining.

As the offerings continue to expand and more women become comfortable with the idea of treatment, Dr. Hamori asserted that there is a direct connection to patient happiness and confidence. “As symptoms subside, women openly share their experiences and gratitude for their improved life, which makes me, as a doctor, very happy.”

References:

1. https://www.businesswire.com/news/

home/20210112005901/en/Global-Sexual-Wellness-Market-

Analysis-and-Forecast-2020-2026-Market-Size-is-Expectedto-

Reach-125.1-Billion-by-2026-Rising-at-a-12.4-CAGR---

ResearchAndMarkets.com#:~:text=In%20context%20to%20

sexuality%2C%20the,transmitted%20infections%20and%20

unwanted%20pregnancy

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105838/

3. https://www.mordorintelligence.com/industry-reports/

vaginal-rejuvenation-market

4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451893/

5. https://my.clevelandclinic.org/health/diseases/9123-sexual-dysfunction-in-females

6. https://pubmed.ncbi.nlm.nih.gov/32791349/

7. https://jamanetwork.com/journals/jama/article-abstract/2784960

8. https://bodybybtl.com/solutions/btl-emsella/

9. https://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/endocrinology/erectile-dysfunction/

10. https://gainswave.com/research/

11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230452/          

12. https://pubmed.ncbi.nlm.nih.gov/31348366/

Science-Backed Skincare Reigns in 2022

Article-Science-Backed Skincare Reigns in 2022

Science-Backed Skincare

Doctors 1 skincare.pngU.S. consumer demand for skincare products continues to grow, and aesthetic practices nationwide are looking for ways to position themselves as skincare experts by recommending products and counseling patients. Practices are using cosmeceuticals to optimize outcomes, and some are becoming product retailers.

“Skincare and cosmeceuticals are a field that is constantly expanding and is one of the fastest growing fields in personal care products. In North America, the cosmeceutical products market is forecasted to reach $18 billion by 2025. This is an area where I see constant growth in my practice,” said board-certified dermatologist Rawaa Almukhtar, MD, of Henry Ford Health in Detroit, Mich., who is referring to statistics by the market research company Mordor Intelligence.

The cosmeceuticals market, which includes skincare, such as anti-aging, sun protection, anti-acne, moisturizers, even hair care and oral care, is forecasted to grow at a compound annual growth rate (CAGR) of 8.25% from 2016 to 2026, according to Mordor Intelligence.

Doctors 2 skincare.pngAccording to Kim Nichols, MD, a board-certified dermatologist and the founder of NicholsMD of Greenwich, Conn., SkinLab by NicholsMD, and NicholsMD of Fairfield, skincare is an integral aspect of a dermatology practice, “…whether through a customized regimen or an individualized treatment plan. With skincare products, each initial consultation includes a suggested regimen based on patient’s skin type and concerns. I teach my staff to educate patients on the importance of at-home skincare as well. Half of the battle with any skin condition is maintaining [the] skin’s health in-between visits to the office,” Dr. Nichols shared.

However, knowing what products come to the surface in a sea of options as offering more than hype can be tricky. It comes down to the science, and not all skincare manufacturers have studies to back their claims.

“Providing advice alongside products that are backed by evidence and clinical studies are important services that we can provide to all our patients,” Dr. Almukhtar stated.

Doctors 3 skincare.pngDr. Almukhtar uses skincare for medical dermatology and cosmetic patients and often combines skincare with prescription treatments. She asserted that all the products she recommends have clinical studies behind them that prove safety and positive outcomes.

In Dr. Nichol’s practice, “Products are applied to every patient prior to them leaving the office, regardless of what treatment they have received.

“For example, antioxidants and UV defense are included in every patient’s regimen, so both products are applied after any treatment in the office. Some products are more suitable for certain treatments. Oftentimes, I will apply a hyaluronic acid-based serum after injectables, whereas lasers require a more nourishing post-procedure moisturizer or restorative face mask,” Dr. Nichols continued.

To successfully incorporate skincare into aesthetic practice, it is crucial to include it in the entire patient experience from start to finish, which means putting products on display throughout the office and al­lowing patients to feel the products on their skin, Dr. Nichols explained.

Skincare 1.pngSome Basics

Not all topicals are created equal. “For example, the size of the molecule is important, and that is something we need to look at or ask the companies about. Molecules that are larger than 500 kilodaltons are unlikely to penetrate the skin,” Dr. Almukhtar warned.

“Another thing to pay attention to is the kinds of active ingredients that penetrate into the skin,” she continued. “Now, there is a move toward newer technology that allows for combining multiple active ingredients. Microencapsulation is a technology that protects multiple active ingredients from interacting with each other and protects the active ingredients from environmentally-induced oxidative damage.”

Dr. Almukhtar shed light on a newer technology, Altreno’s Tretinoin Lotion 0.05%. “We recently published a study in the Journal of Drugs in Dermatology that looks at this newer product, a lotion, that combines tretinoin with hyaluronic acid and glycerin in a micro-capsulation method. What we did was combine a non-ablative laser and a 1927 thulium laser with this tretinoin product. This significantly improved facial photodamage, and it was well-tolerated by patients,”1 Dr. Almukhtar emphasized.

Skincare 2.pngPhysicians Taking Charge

Oculoplastic surgeon Christopher Zoumalan, MD (Beverly Hills, Calif.) took it upon himself to create clinically investigated and “properly evaluated” products to enhance skin healing. Today, he not only practices but is also the inventor, founder and CEO of the Skinuva line of products.

“When I was looking around for the best scar cream to provide to my patients after eyelid surgery or any other surgery that I perform, I could not find a product that was backed by clinical data,” Dr. Zoumalan noted. “That is when I started to think outside the box as a physician and scientist. I started to investigate potential ingredients that can help improve scarring and found there were so many of them, but they were not included in scar products.”

As a result, he developed Skinuva Scar Cream, which includes synthetic growth factors, which are powerful when used correctly. Dr. Zoumalan pointed out that a scar treatment product needs to contain the right amount of specific growth factors to target wound healing successfully.

“Studies have shown this product improves the scar’s redness, hyperpigmentation and thickness. I included centella asiatica, aloe vera, selective growth factors, hyaluronic acid, vitamin C and silicone cream. Once I developed this product, my colleagues and I conducted clinical trials, including one that was published in the Aesthetic Surgery Journal. We found that it was nearly two times more effective in improving scars compared to traditional silicone cream,”2 Dr. Zoumalan reported.

Dr. Zoumalan recommends starting use of the cream about two weeks after procedures that can cause wounds and scars. “Two weeks post-surgery is usually when scar contraction starts to occur and applying the cream directly on the incision during this time is ideal for optimal wound healing. In order to get the best results, you can use it twice a day for up to three to six months after surgery,” he expanded.

The product has also been clinically studied to support its safety and efficacy in wound healing after CO2 laser resurfacing, chemical peels and microneedling.

Another physician pioneer in the skincare space is dermatologist Carl Thornfeldt, MD, founder of Epionce (Boise, Idaho). He also believed that skincare products must be backed by the kind of clinical studies that physicians expect to see.

The company’s skincare portfolio includes clinically proven Epionce Luminous Eye Serum + Renewal Eye Cream. This anti-aging eye duo blends brightening botanicals, multiple algae extracts and barrier-repairing lipids to reduce under-eye puffiness, increase visible firmness, diminish dark circles and improve the appearance of fine lines and wrinkles. In a study, 95.7% of panelists experienced highly statistically significant improvement in under-eye puffiness at 14 weeks. The retinol-free duo addresses the unique challenges of the eye area – without irritation – while enhancing hydration, repair and protection from environmental pollutants, including blue light according to Epionce.

Skincare 3.pngTop Practice Categories and Recommendations

The essential topical skincare categories for practices to consider include cleansers, moisturizers, sunscreen and antioxidants, according to Dr. Almukhtar. “These are the general products that I recommend to my patients regardless of whether they are doing a procedure or not,” she shared.

Among the antioxidant products that Dr. Almukhtar recommends are SkinCeuticals C E Ferulic Antioxidant Serum and SkinCeuticals Phloretin CF, containing phloretin, vitamin C (l-ascorbic acid) and ferulic acid. The second of which Dr. Almukhtar is likely to recommend to acne-prone patients because it does not have vitamin E. She also recommends Revision Skincare C+ Correcting Complex and Melatonik by ISDIN, which has melatonin, bakuchiol and vitamin C.

“In addition to those products, for day-to­day at-home use I recommend some topicals based on certain indications that patients are coming in for – anti-aging, acne, rosacea, melasma – or if they are having a procedure in the office,” Dr. Almukhtar noted.

Skincare 4.pngCombining Procedures and Skincare

Dr. Almukhtar might recommend a product that enhances healing and collagen building for pa­tients that have procedures with ablative or non-ablative lasers, energy-based devices or microneedling. “I incorporate a topical that has growth factors and peptides to boost the patient’s ability to grow collagen during the healing process,” she stated.

Products that have research suggesting they help build collagen include Skin Medica’s TNS Recovery Complex, which features a fibroblast culture derived from neonatal foreskin, which is rich in growth factors, explained Dr. Almukhtar.

“I recommend a product that has TriHex technology (Alastin), a proprietary blend of active ingredients that stimulate collagen and elas­tin synthesis and stimulate wound healing,” Dr. Almukhtar added. “Another technology that stimulates collagen building is a peptide called defensins, combined with a type of stem cell found in hair follicles called LGR6+ (DefenAge), these stem cells are responsible for producing keratinocytes in the epidermis.”

Dr. Almukhtar tends to use these products af­ter procedures, with some exceptions. “One of the products with TriHex technology has a study that shows if we use the product for three weeks before and after laser resurfacing the procedure results in higher patient satis­faction; this is an effect of the increased colla­gen and elastin building capacity of the skin,”3 Dr. Almukhtar reported.

Skincare 5.pngMichael H. Gold, MD, medical director of the Gold Skin Care Center and Tennessee Clinical Research Center in Nashville, Tenn., says Alastin’s Regenerating Skin Nectar with TriHex Technology (Carlsbad, Calif.) is the company’s hero product.

“We did a study (now published) looking at microneedling on the neck, and the results showed that when you use [the Regenerating Skin Nectar] compared to [place­bo], the healing was much faster. It is a great post-procedure product; whether it is laser or microneedling it works great,”4 Dr. Gold remarked.

Akis Ntonos, FNP-C, founder of Aion Aesthetics in New York City, N.Y., uses AnteAGE MD Serum & Accelerator from AnteAge (Irvine, Calif.) to enhance outcomes from in-office treatments.

AnteAGE MD supplies medical-grade solutions exclusively made for providers to treat the skin with anti-inflammatory growth fac­tors derived from human bone marrow stem cells. According to Mr. Ntonos, the system provides exceptional results at a cellular level. “The aqueous formula contains two growth factors TGF-3 and IGF-1,” he expressed. “The system utilizes 21 clinically proven ingredients to enhance healing and provide anti-inflammatory benefits.

“The AnteAGE Serum & Accelerator are used in practice after various treatments such as neurotoxin or filler injections, but they are for at-home use,” Mr. Ntonos continued. “Patients utilize them morning and night by applying the serum first, followed by the ac­celerator. I suggest that my patients incorporate them in their daily routine.”

Mr. Ntonos said he specifically loves the Accelerator, “because it utilizes bakuchiol, a natural, non-irritating alternative to retinol. This makes this skincare routine acceptable for all skin types without the need for multiple products.”

Skincare 6.pngEMC Pharma’s (Maryland Heights, Mo.) products feature hypochlorous acid (HOCl), which has been shown to eradicate bacteria, reduce inflammation, reduce pruritus, break down biofilm and increase oxygenation. The company has several products in its skincare portfolio including Levicyn Dermal Spray, Levicyn Spray Gel, Celacyn Scar Gel, Acuicyn Eyelid and Eyelash Cleanser, Epicyn and Sebuderm.

“The Levicyn Dermal Spray is a go-to product for about everything we do in the clinic,” Dr. Gold stated. “Levicyn is hypochlorous that destroys almost every [bacterium], fungus and virus known to man. During procedures, it keeps the areas that we are working with clean. You can even put it around the eyes and mouth without consequence, it is not going to hurt anything. I actually keep a bottle on my desk to spray it after I have been in patient rooms, just to keep things clean.”

Dr. Gold also uses the Celacyn Scar Gel. “It has a special delivery system that works really nicely to help reduce the appearance of scars. For raised, old scars, it works really well,” he highlighted.

Managing Photodamage and More

Today’s sunscreens are providing more than just sun protection, according to Dr. Almukhtar. “We published research in the Journal of Drugs in Dermatology looking at a sunscreen that contains peptides, antioxidants and a proprietary enzyme that repairs DNA damage from the sun. The product is called ISDIN Eryfotona Actinica, and the results from the study showed that after 12 weeks of use on the face, there was an 81% improvement on the Investigator Global Aesthetic Improvement Scale. Specifically, investigators noted improvement in skin radiance, facial aesthetics and evenness of skin tone,”5 Dr. Almukhtar reported.

There is growing evidence to support active ingredients other than hydroquinone for addressing pigmentation concerns.

SKincare 7.png“I tend to recommend hydroquinone-free products,” Dr. Almukthar stated. “There are a few on the market that are backed by evidence. The most common ingredients are tranexamic acid, kojic acid, niacinamide and cysteamine. Examples of products that are tested and will help with pigmentary issues are Lytera 2.0 by SkinMedica, which has tranexamic acid, resorcinol and niacinamide; Discoloration Defense by SkinCeuticals, which has tranexamic acid, niacinamide and Kojic acid; and Cyspera by Scientis, which includes cysteamine. Dr. Almukthar said she tends to use Lytera 2.0 or Discoloration Defense after a laser procedure targeting pigmentation. “Usually, it can be used immediately after the procedure, and patients can continue the treatment for a few weeks until I see them for follow-up.”

Dr. Zoumalan developed Skinuva Brite out of frustration with hydroquinone.

Skinuva Brite uses specific types of synthetic growth factors, along with other clinically proven ingredients that help improve hyperpigmentation. These include tranexamic acid, niacinamide, arbutin and vitamin C.

“Growth factors are potential messengers that help signal our cells to react and respond,” Dr. Zoumalan began. “When it comes to hyperpigmentation, there are certain growth factors that, when elicited, cause more of a melasma reaction or more of a hyperpigmentation re­sponse. You do not want to use those growth factors, rather you would want to use the ones that help regulate and improve hyperpig­mentation. One is an epidermal growth factor, which is very well studied.”

“Furthermore, when applied topically, evi­dence suggests that tranexamic acid is al­most equal in efficacy to hydroquinone. Nevertheless, it has to be properly formulated to ensure its stability,” Dr. Zoumalan cau­tioned. “The percentage you use is also im­portant. We did a head-to-head clinical trial published in the Journal of Cosmetic Science comparing the Skinuva Brite product to hydro­quinone 4% and found that our product did better with zero adverse reactions.”

SKincare 8.pngAdvances in Skincare “Technology”

Biocell Collagen® CG from Modere (Miami, Fla.) is based on the multi-patented Collagen/HA Matrix® Technology featured in the company’s best­selling product, Liquid BioCell®. This naturally co-existing matrix of hyaluronic acid and collagen peptides is enhanced with a patented Bio-Optimized™ process to help ingredients absorb into the surface layers of skin for maximum benefits.

Hyaluronic acid helps deeply hydrate the skin for a plumper, more youthful appearance. Type II collagen helps improve elasticity and firmness, but in their natural state, collagen molecules are too large to be effectively absorbed by the body. The Bio-Optimized manufacturing process achieves the ideal molecular weight – even beyond what typical hydrolyzed collagen can offer.

EXOVEX from Exocel Bio (Doylestown, Pa.) is an­other example of technology advancing skincare.

EXOVEX uses a proprietary incubation medium and a stringent process to produce high po­tency and safe exosomes. It is a companion product for skin and hair rejuvenation, used post-microneedling or with energy-based aesthetic applications. The non-lyophilized, live exosomes with growth factors, and miRNA in the product help reduce the signs of aging, according to Exocel Bio.

Glynis Ablon, MD, associate clinical professor at UCLA and founder of the Ablon Skin Institute & Research Center in Manhattan Beach, Calif., typically uses EXOVEX with microneedling and fractionated lasers, “but I just started applying it with dermo electroporation or needleless applications,” she shared. “My patients quickly notice after a few days how their skin is glow­ing while looking smoother and softer.”

Skincare 9.pngSkincare or Cosmetic Procedure?

RegenPRP + ATS is an example of how skincare and aesthetic procedures meet in the middle. The RegenKit, patented gel-based separation technology, from RegenLab (Brooklyn, N.Y.), is the secret behind this medical device’s abil­ity to provide the standardized preparation qualified as RegenPRP. The precision of the proprietary neutral thixotropic polymer in iso­lating blood components allows for a solution with a constant acellular profile, explained a RegenLab representative.

“Everyone knows about platelet-rich plasma (PRP), but ATS stands for Autologous Thrombin Serum. This serum is collected from the patient using RegenLab devices. The same applies to the collection of the PRP, which is done simultaneously,” said Sandrine Grept-Locher, MD, an aesthetic medicine specialist at SGL Esthethique in Geneva, Switzerland.

“When I mix the standard PRP with the ATS, the coagulation cascade is activated, transforming the standard PRP into a solid gel that will serve as a matrix for the release of growth and chemotactic factors at the injection sites. I will then use this gel as a tissue filler and regenerator,” she explained.

Treatment triggers a skin rejuvenation process, smoothing wrinkles and fine lines. It fills in volume loss in certain areas of the face, such as nasolabial folds and dark circles, Dr. Grept-Locher illustrated.

PRX-T33 Derm Perfexion is another such example.

Marketed by Love Beauty Pro & Medical (Woburn, Mass.), this regenerative aesthetic treatment combines the effects of hydrogen peroxide, 33% TCA and kojic acid. It is a no-downtime and no photosensitivity treatment that is safe for all skin types and targets aging skin, texture, laxity, wrinkles and dull skin for complete rejuvenation of the face and body, according to Derm Perfexion.

For Ginger L. Urbaniak, MD, of Urbaniak Plastic Surgery & Medical Spa in Clearwater, Fla., PRX-T33 has been a game-changer for treating skin. “We have seen skin laxity improvement along the jawline, over the cheeks and even repair of stubborn wrinkles,” she noted. “As an injector, I have seen my filler perform better for fine lines and wrinkles because the skin is healthier and firmer.”

On the body, Dr. Urbaniak said the abdomen and arms are favorite areas to treat. “We pair this with our medical grade skincare focusing on brightening and tightening,” she shared. “The PRX has kojic acid, so the treatments are a great jumpstart to reverse the signs of sun damage as well.”

Consider Passing on These Products

Dr. Almukhtar does not recommend toners because many are astringents, which can contain high levels of alcohol. “Toner can compromise the skin barrier, and there is no added benefit of adding a toner into a regimen if the patient is already on a good cleanser.

“Another ingredient that I try to get patients away from would be essential oils,” Dr. Almukhtar continued. “These are products that can have multiple ingredients in them that are sensitizing to the skin, and I often see either allergic or irritant contact dermati­tis from such products.”

One other product that might be more trouble­some than beneficial is coconut oil on an acne-prone patient. “While coconut oil might help a patient with eczema, it can cause breakouts on those who get acne,” stated Dr. Almukhtar.

Expect More from Skincare’s Future

Advances in how skincare is formulated will likely continue to improve penetration of ac­tive ingredients and reduce irritation, accord­ing to Dr. Almukhtar.

“I think more clinical studies will happen on different skin types and various ethnic backgrounds that would help individualize those in the future,” she speculated.

References:

1. Almukhtar, R., Carr, E., Angra, K., Lipp, M., Boen, M., & Goldman,

M. (-1, November 30). Single-center, prospective, double-blind, evaluator-blind, non-randomized, vehicle-controlled trial with a 1927 nm non-ablative fractionated laser and topical 0.05% tretinoin lotion for facial dyspigmentation and Photodamage

-JDDonline - Journal of Drugs in dermatology. JDDonline. Retrieved July 27, 2022, from https://jddonline.com/articles/

single-center-prospective-double-blind-evaluator-blind-non­randomized-vehicle-controlled-trial-with-S1545961621P1174X/

2. Zoumalan CI, Tadayon SC, Roostaeian J, Rossi AM, Gabriel

A. Safety and Efficacy of a Scar Cream Consisting of Highly Selective Growth Factors Within a Silicone Cream Matrix: A Double-Blinded, Randomized, Multicenter Study. Aesthet Surg J. 2019 Feb 15;39(3):319-330. doi: 10.1093/asj/sjy185. PMID: 30084900.

3. Vanaman Wilson, MJ, Bolton, J, Fabi, SG. A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face. J Cosmet Dermatol. 2017; 16: 217– 222. https://doi.org/10.1111/jocd.12339

4. Gold, MH, Sensing, W, Biron, JA. A topical regimen improves skin healing and aesthetic outcomes when combined with a radiofrequency microneedling procedure. J Cosmet Dermatol. 2019; 18: 1280– 1289. https://doi.org/10.1111/jocd.13037

5. Kern, J. A., Wood, E., Almukhtar, R., Angra, K., Lipp, M., & Goldman, M. (-1, November 30). Evaluation of an SPF50 sunscreen containing photolyase and antioxidants for its anti-photoaging properties and photoprotection - jddonline-journal of drugs in dermatology. JDDonline. Retrieved July 27, 2022, from https://jddonline.com/articles/evaluation-of­an-spf50-sunscreen-containing-photolyase-and-antioxidants­for-its-anti-photoaging-prop-S1545961622P0517X/

6. Kalasho BD, Minokadeh A, Zhang-Nunes S, Zoumalan RA, Shemirani NL, Waldman AR, Pletzer V, Zoumalan CI. Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study. J Cosmet Sci. 2020 Sep/Oct;71(5):263-290. PMID: 33022197.

Cash Relief Still Available to the Medical Aesthetic Industry

Article-Cash Relief Still Available to the Medical Aesthetic Industry

Cash Relief Still Available to the Medical Aesthetic Industry

The medical aesthetic industry was significantly impacted during the pandemic. Surgical and nonsurgical medical aesthetic practices experienced full and partial shutdowns due to governmental orders, only to reopen subject to suffocating capacity restrictions and sanitation procedures. Luckily, the entire industry still has the opportunity to access significant cash relief in a refundable employee payroll tax credit – the Employee Retention Credit (ERC).

With credits often exceeding the initial payroll tax liabilities, the ERC has already awarded millions of dollars to a broad spectrum of employers, including those in the medical aesthetic industry. Unlike the Paycheck Protection Program (PPP) loans, the ERC was never limited by available federal funds, so any practice that qualifies, and applies, can still find ERC relief.

Launched in March 2020, the ERC remains one of the biggest relief opportunities – up to $26,000 per employee during 2020 and 2021 – available to businesses that have been negatively impacted by the Covid-19 pandemic. Even for those businesses already beginning to recover, employers can retroactively claim the ERC based on hardships experienced during 2020 and the first three quarters of 2021.

Employers should also remember: The ERC is available even if they already received PPP loans, and, businesses that started up after February 2020 may qualify under specific ERC provisions that can provide up to $100,000 in refundable credits in 2021.

What is the ERC?

Introduced in the CARES Act, and intended to incentivize employee retention during the pandemic, the ERC is:

  • A refundable payroll tax credit
  • Claimed quarterly
  • Reducing payroll taxes/producing cash refunds
  • Available to both eligible for-profit and not-for-profit employers who retained W-2 employees

ERC Eligibility

Employers in the medical aesthetic industry are typically eligible because government orders restricted their operations.

Common examples include, but are not limited to, orders that:

  • Prohibited elective procedures
  • Prevented medical device companies from physically entering premises to install/ service devices used in medical aesthetic practices
  • Imposed capacity restrictions in waiting rooms or even limited the number of patients permitted to be treated in a day
  • Spacing limitations
  • Reductions to hours of medical practices to comply with hygiene/sanitation procedures

Note that orders creating qualifying partial suspensions were more common than many employers and tax practitioners realize.

Another way for employers in the industry to be eligible is by showing that their business suffered a reduction in gross receipts.

1. Tax Year 2021 (Q1, Q2 and Q3)
The employer is eligible if the business’s gross receipts are more than 20% down from the gross receipts in the same calendar quarter of 2019.

2. Tax Year 2020 (Q1-Q4)
The employer is eligible if the business’s gross receipts are more than 50% down from the gross receipts in the same calendar quarter of 2019.

Conclusion

Remember, although many other forms of government pandemic relief are depleted, the ERC remains available now. Numerous government orders restricted a myriad of ordinary business operations in the industry – and you may be one of many employers entitled to substantial cash benefits. If you operate a business in the cosmetic and beauty industry, find out if you qualify.

Editor's Note: Frost Law recognizes this credit s unprecedented reach and potential for employers in the medical aesthetic industry who retained W-2 employees throughout the pandemic. While many CPA firms and other professionals are missing this credit entirely, or do not have the time to dedicate to the nuanced analysis required in each case, Frost Law has devoted significant time and resources to understanding the ERC. Frost Law’s dedicated team of attorneys have been working with employers who need this relief.

 

About the Author

Glen FrostGlen Frost
Mr. Frost is a managing partner of Frost Law (Washington, D.C.), a tax law firm focused on Tax, Estate, Business, Litigation & Civil, Bankruptcy, Employment and Family Law. He holds an LL.M in taxation, is a licensed attorney, a certified public accountant, and a certified financial planner®. The Frost Law team provides tax planning advice on a variety of issues, and represents clients in tax collection, tax examination, tax appeal matters pending before the IRS, and in civil and criminal litigation in U.S. Tax Court, U.S. District Court and State Courts.